You can take it with or without food, depending on your personal preference. You should not change your dose or take it at a different time of day without speaking to your provider first. Avoid drinking alcohol, driving, and engaging in any potentially dangerous activities while taking Provigil. Store your Provigil at room temperature, and ensure that the pill bottle is out of reach of children and pets.
Provigil is used off-label to treat fatigue or sleepiness associated with the following conditions:. Off-label use means that even if a drug is not FDA approved to treat a particular condition, a healthcare provider can still prescribe it if they judge it to be medically appropriate.
Provigil may begin to work within 30 minutes of taking it and reaches peak blood levels within one to two hours. This is not a complete list of side effects and others may occur. A medical professional can advise you on side effects. If you experience other effects, contact your pharmacist or a medical professional. You may report side effects to the FDA at www.
Like other medications, Provigil can cause side effects. Tell your healthcare provider about any side effects you experience while using Provigil, especially if they persist or worsen. The most common side effects of taking Provigil include:. Potential severe side effects of Provigil include:.
Call your healthcare provider right away if you have severe side effects. Provigil may cause other side effects. Call your healthcare provider if you have any unusual problems while taking this medication. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine.
Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. There are no specific Provigil dosing adjustments for adults with kidney disease or mild to moderate liver impairment. For adults with severe liver impairment, the manufacturer recommends reducing the Provigil dose to one-half of that recommended for patients with normal liver function.
There are no specific Provigil dosing adjustments for older adults aged 65 years or older. Yet, since Provigil may be processed more slowly in older individuals, healthcare providers often start at a lower dose and monitor more closely for side effects. Be sure to tell your provider if you are pregnant or planning to become pregnant. Animal studies suggest that Provigil may cause harm to the baby. In that case, skip the dose and go back to your usual dosing schedule.
Taking Provigil too late in the day might cause problems sleeping that night. Do not ever double-up on doses. If you find that you are missing Provigil doses often, consider setting an alarm on your phone, purchasing a pillbox, or asking a loved one or friend to remind you when to take your dose. Taking more than the maximum recommended dose of Provigil can cause unpleasant side effects. There is no specific antidote to treat a Provigil overdose. Supportive care, including heart monitoring, may be warranted in some cases.
Symptoms of a Provigil overdose can include:. If you think you or someone else may have overdosed on Provigil, call a healthcare provider or the Poison Control Center Your doctor should check your progress at regular visits to make sure that this medicine is working properly. Your blood pressure may need to be checked more often while taking this medicine.
It is important to tell your doctor if you become pregnant. Your doctor may want you to join a pregnancy registry for patients taking this medicine. Serious skin reactions can occur with this medicine. Stop using this medicine and check with your doctor right away if you have blistering, peeling, or loosening of the skin; red skin lesions; severe acne or skin rash; sores or ulcers on the skin; or fever or chills while you are using this medicine. This medicine may cause you to have a serious type of allergic reaction called anaphylaxis.
Anaphylaxis can be life-threatening and requires immediate medical attention. Stop taking this medicine and call your doctor right away if you have a skin rash; itching; hives; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are using this medicine. This medicine may cause serious allergic reactions affecting multiple body organs e.
Stop using this medicine and check with your doctor right away if you have the following symptoms: chest pain or discomfort, fever and chills, dark urine, headache, rash, stomach pain, unusual tiredness, unusual bleeding or bruising, or yellow eyes or skin.
If you think modafinil is not working properly after you have taken it for a few weeks, do not increase the dose. Instead, check with your doctor. If you are using a medicine for birth control such as birth control pills, implants, shots, patches, vaginal rings, or an IUD , it may not work properly while you are taking modafinil.
To keep from getting pregnant, use another form of birth control while you are using this medicine and for one month after your last dose. Other forms of birth control include condoms, diaphragms, or contraceptive foams or jellies. For most people, it usually takes 30 to 60 minutes to start working. If you take Provigil with food, it might take slightly longer.
Modalert is another name for Provigil. This form of Provigil is sold in countries outside of North America. For most people who take Provigil as prescribed by their doctor, it continues to work even when taken for long periods of time. They may need to increase your dosage or consider a different medication. If you think you or your child has taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at or through their online tool.
But if your symptoms are severe, call or go to the nearest emergency room right away. When Provigil is dispensed from the pharmacy, the pharmacist will add an expiration date to the label on the bottle.
This date is typically one year from the date the medication was dispensed. However, an FDA study showed that many medications may still be good beyond the expiration date listed on the bottle. How long a medication remains good can depend on many factors, including how and where the medication is stored. Provigil should be stored at room temperature.
If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. Before taking Provigil, talk with your doctor about your health history.
Provigil may not be right for you if you have certain medical conditions. These include:. Provigil is a stimulant with effects dissimilar compared to other central nervous stimulants such as amphetamine or methylphenidate. Provigil does not have alpha-adrenergic effects, but the alpha-adrenergic antagonist prazosin can decrease the wakefulness effects of Provigil. Provigil dopamine reuptake does not have dopamine receptor agonist activity.
Dopamine antagonists do not block wakefulness from Provigil. Animal studies show that Provigil increases glutaminergic activity in the thalamus and hippocampus. Provigil is readily absorbed when taken orally and reaches peak plasma concentration within 2 to 4 hours.
Peak levels may be delayed by about an hour when the drug is taken with food. Provigil is primarily eliminated via the liver. Provigil induces cytochrome P 3A4 and induces its own metabolism through this route. Provigil is contraindicated in people who have had a hypersensitivity reaction to Provigil or Nuvigil armodafinil in the past. Provigil is a Schedule IV controlled substance. Studies show that Provigil has the potential to cause euphoric effects and feelings consistent with other stimulants, including methylphenidate.
People with a history of alcohol or drug abuse may have a higher risk of abusing Provigil. Disclaimer : MedicalNewsToday has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date.
However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional.
You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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Measure content performance. Develop and improve products. List of Partners vendors. Modafinil, also known by its brand name Provigil, is a central nervous stimulant that has been approved by the U.
Food and Drug Administration to treat daytime sleepiness in individuals who have conditions that include narcolepsy, shift work disorder, and sleepiness caused by medical conditions such as sleep apnea.
However, it is also sometimes misused without a prescription. Plenty of people misuse cognitive-enhancing or psychostimulant drugs in a nonprescription capacity in order to increase productivity, combat fatigue, and help with intellectual challenges. However, it is not uncommon for other groups of people to misuse these drugs as well. For example, 8. Modafinil is supposed to be less addictive than other psychostimulants like amphetamine, but some evidence suggests that dependence and abuse are possible.
Modafinil is sometimes called a "wakefulness-promoting agent. Modafinil affects the hypothalamus, hippocampus, and amygdala which are parts of the brain.
Modafinil is a tablet taken by mouth usually once-a-day. However, shift workers who take the drug to promote wakefulness take the drug before their shifts begin. Modafinil is used to treat problems with sleep, arousal, and wakefulness. Some conditions treated with modafinil include the following:. Modafinil's most common adverse effects include the following:. Other adverse effects include the following:. Some of these adverse effects are scary and dangerous so be sure to contact your physician if you experience any of them.
If you are having suicidal thoughts, contact the National Suicide Prevention Lifeline at for support and assistance from a trained counselor. If you or a loved one are in immediate danger, call For more mental health resources, see our National Helpline Database. Additionally, some of these adverse effects such as insomnia, restlessness, chest pain, nausea, and confusion may result from overdose with modafinil. If you suspect an overdose, call emergency services or contact a physician immediately.
Modafinil isn't for everyone, and before your physician prescribes you this medication, you should inform her of the following:.
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